On 7 February 2021, the Minister of Health of the Democratic Republic of the Congo declared an outbreak of Ebola Virus Disease (EVD) after the laboratory confirmation of one case in North Kivu Province. The case was an adult female living in Biena Health Zone. To date the source of infection is still under investigation.

On 25 January 2021, the case presented with nasal bleeding. From 25 January to 1 February, she reportedly received outpatient care at a local health centre. From 1 to 3 February, she was admitted to a second health centre with signs of physical weakness, dizziness, joint pain, epigastric pain, liquid stools, headache and difficulty breathing. On 3 February, a blood sample was collected for EVD testing due to her epidemiological link with an EVD survivor. On the same day, she was referred to a hospital in Katwa Health Zone (part of Butembo city) following the deterioration of her condition. She was admitted to the intensive care unit the same day and died on 4 February. On 5 February, the body was buried in Musienene Health Zone, however not under safe burial practices.

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